Dr Chris Barnes
MBBS, FRACP, FRCPA - Clinical and Laboratory Haematologist

Dr Chris BarnesChris Barnes received medical training at Monash University before training in paediatric haematology and oncology at the Royal Children’s Hospital. He completed clinical and laboratory haematology training at the Royal Melbourne Hospital. Chris has trained overseas at the Hospital for Sick Children, and St Michaels Hospital, Toronto, Canada where he trained as a clinical fellow in haemostasis and thrombosis.

Chris has a particular interest in the diagnosis and management of non – malignant haematological conditions including thrombosis and bleeding disorders.

Chris is currently employed as a consultant haematologist at the Royal Women’s and Royal Children’s Hospital, and is a non-malignant haematologist at Cabrini Hospital, Malvern. He is currently Director of the Henry Ekert Haemophilia Treatment Centre at the Royal Children’s Hospital in Melbourne.

Chris consults privately at the Royal Childrens Hospital and Cabrini Hospital, Malvern.


Current Positions        

  • Consultant Haematologist Royal Childrens Hospital and Royal Women’s Hospital
  • Director, Henry Ekert Haemophilia Treatment Centre
    Royal Childrens Hospital
    Flemington Road
    Parkville 3052
    Australia
  • Haematologist, Cabrini Medical Centre
    Suite 26,
    Cabrini Medical Centre
    183 Wattletree Road
    Malvern 3144
  • Senior Lecturer (Honorary)
    Department of Pathology
    University of Melbourne
    Melbourne

Degrees and Professional Qualifications

  • M.B., B.S. (Honours) Monash University
  • Fellow Royal Australian College of Physicians
  • Fellow Royal College of Pathologists of Australasia

 

Publications

Peer Reviewed Manuscripts

  1. Barnes, C Deidun, D Hynes, K Monagle, M. “Alopecia and Dalteparin; a previously unreported association”. Blood. 2000 96: 1618-1619.
  2. Barnes, C Rudzki, R and Ekert, R “Induction of Immune Tolerance and Suppression of Anaphylaxis in a Child with Haemophilia B by simple Plasmapheresis and Antigen Exposure”. Haemophilia. 2000 6(6) 693 - 695
  3. Barnes, C Berkowitz, R Curtis, N Waters, K. “Aspergillus infection of the larynx in a six-year-old girl following bone marrow transplantation”. International Journal of Pediatric Otorhinolaryngology 2001 Vol 59/1,pp 59-62
  4. Barnes, C Monagle P. “Hemostatic changes following the modified Fontan procedure”. Letter to the Editor. Thrombosis and Haemostasis. Nov 2001, 86(5) p1341-2
  5. Barnes, C Brewin, T Ekert H. “Induction of immune tolerance and suppression of anaphylaxis in a child with haemophilia B by simple plasmapheresis and antigen exposure: progress report.”. Haemophilia. 7(4):439-40, 2001 Jul.
  6. Barnes, C Newall, F Monagle, P. “Post Thrombotic Syndrome”. Archives of Diseases in Childhood 2002; 86: 212-214.
  7. Barnes, C Sizeland, A Berkowitz,R Sexton, M Tiedemann, K Waters, K “Laryngeal Carcinoma in Children”. International Journal of Pediatric Otorhinolaryngology 2001 Vol 61 83 - 86
  8. Barnes, C Newall, F Carden, S Higgins, S and Monagle P. “Perinatal management of patients at high risk of protein C deficiency”. Thromb Haemost. 2002 Aug;88(2):370-1
  9. Barnes, C Newall, F and Monagle, P. Thrombembolic complications related to indwelling central venous catheters with oncological/haematological diseases: a retrospective review of 362 catheters. [Letter] Supportive Care in Cancer. 10(3):256-7, 2002 Apr.
  10. Barnes, C Downie, P Chalkiadis, G Camilerri, S Waters, K. “Current Sedation Practices for Paediatric Oncology Patients having diagnostic or therapeutic procedures; An ANZCCSG group wide survey”. Journal of Paediatrics and Child Health. 38 (2) 170 – 173 2002.
  11. Barnes, C Igjnatovic, I Newall, F Carlin, J Ng, F Hamilton, S Ashley, D Waters, K and Monagle, P. Change in serum procalcitonin (ΔPCT) predicts the clinical outcome of children admitted with febrile neutropenia. British Journal of Haematology 118(4):1197-8, 2002 Sep
  12. Newall, F Barnes, C Ignatatovic, I and Monagle, P “Heparin Induced Thrombocytopenia in Children”. Journal of Paediatrics and Child Health 39(4) 289 – 293 2003
  13. Barnes, C Newall, F Monagle, P. “Post Thrombotic Syndrome”. Phlebology Digest 4(16) 14 – 17 2003
  14. Barnes, C Newall, F Furmedge, J Mackay, M and  Monagle P “Cerebral Sinus Venous Thrombosis”. Journal of Paediatrics & Child Health. 40(1-2):53-5, 2004 Jan-Feb.
  15. Barnes, C Monagle, P McNamara, J “Velcroholism” Journal of Paediatrics and Child Health. 39(5):392, 2003 Jul.
  16. Barnes, C Newall, F Harvey, S and Monagle, P “Interpretation of thrombophilia in childhood stroke – a cautionary tale” Journal of Child Neurology. 19(3):218-9, 2004 Mar
  17. Newall, FH, Barnes, C, Savoia, HF, Campbell, J, Monagle, P. Warfarin therapy in children requiring long term Total Parenteral Nutrition (TPN). Pediatrics. 112(5):e386, 2003 Nov
  18. Barnes, C Hogan, C Antippa, P and Tuckfield , A “Penetrating Injury to the Heart in a Patient with Haemophilia” Volume 10, Issue 1, Page 101-101, Jan 2004
  19. Ignjatovic, I Barnes, C Newall, F Hamilton, S Burgess, J Monagle, P  “Point of Care Monitoring of Oral Anticoagulant Therapy in Children: Comparison of CoaguChek Plusâ and Thrombotestâ Methods with Venous International Normalised Ratio” Thrombosis & Haemostasis. 92(4):734-7, 2004 Oct.
  20. Barnes, C Newall, F Furmedge, J MacKay, M and Monagle, P “Arterial Ischaemic Stroke in Children” Journal of Paediatrics & Child Health. 40(7):384-7, 2004 Jul.
  21. Barnes, C Wong, P Egan, B Speller, T Cameron, F Jones, G Ekert, H and Monagle, P “Reduced bone density in children with severe haemophilia” Pediatrics. 114(2):e177-81, 2004 Aug.
  22. Barnes, C Newall, F Ignjatovic, V Wong, P Cameron, F Jones, G and Monagle, P “Reduced bone density in children on long-term warfarin” Pediatric Research. 57(4):578-81, 2005 Apr.
  23. Barnes, C Gerstle, J T Freedman, M H Carcao, M D “Clostridial septicum infection in children with congenital neutropenia”. Pediatrics. 114(6):e757-60, 2004 Dec.
  24. Monagle, P Newall, F Barnes, C Savoia, H Campbell, J and Crock, C “A Prospective Registry of Arterial Thromboembolic Disease in Infants and Children: the Clinical Impact.” Submitted to New England Journal of Medicine
  25. Barnes, C Blanchette, V Canning, P and Carcao, M “Recombinant FVIIa in the management of intracerebral haemorrhage in severe thrombocytopenia unresponsive to platelet enhancing treatment.” Transfusion Medicine. 15(2):145-50, 2005 Apr.
  26. Barnes, C Deveber, G “Prothrombotic abnormalities in childhood ischaemic stroke” Thrombosis Research. 118(1):67-74, 2006.
  27. Barnes, C, G E Rivard, M-C Poon, J Teitel, M Pai, M Kern, V Blanchette and M Carcao on behalf of the Inhibitor Subcommittee of the Association of Hemophilia Clinic Directors of Canada. “Canadian multi-institutional survey of immune tolerance therapy (ITT) – experience with the use of recombinant factor VIII for ITT” Haemophilia. 12(1):1-6, 2006 Jan.
  28. Davis, M and Barnes, C “Thrombotic Thrombocytopenic Purpura in Childhood: an uncommon but life-threatening cause of thrombocytopenia”. Submitted to Journal of Paediatrics and Child Health.
  29. Kelsey, G Monagle P and Barnes, C “Delayed Diagnosis of Congenital Factor IX deficiency (Christmas disease) in a girl with Turner’s Syndrome”. Clinical & Laboratory Haematology. 28(5):355-6, 2006 Oct.
  30. Monagle P. Barnes C. Ignjatovic V. Furmedge J. Newall F. Chan A. De Rosa L. Hamilton S. Ragg P. Robinson S. Auldist A. Crock C. Roy N. Rowlands S. Developmental haemostasis. Impact for clinical haemostasis laboratories. Thrombosis & Haemostasis. 95(2):362-72, 2006 Feb.
  31. Price V. Barnes C. Canning P. Blanchette V. Greenberg M. Immune thrombocytopenia following successful treatment of cancer in children. Pediatric Blood & Cancer. 46(3):372-6, 2006
  32. Barnes, C Blanchette, V Lillicrap, D Mann, K Stain, AM Leggo, J Hilliard, P and Carcao, M “Different clinical phenotype in triplets with haemophilia A” Haemophilia March 2007 - Vol. 13 Issue 2 Page 202 – 205
  33. Egan, B Eldridge, B Barnes, C and Wolfe, R “Measurement of physical activity in boys with haemophilia using a remote activity monitor” Submitted to Haemophilia
  34. Barnes, C Davis, A Furmedge, J Egan, B Donnan L and Monagle, P “Induction of immune tolerance using Rituximab in a child with severe haemophilia B with inhibitors and anaphylaxis to factor IX.” Haemophilia In press
  35. Peak, L Francis, D and Barnes, C “Urgent arterial – venous fistula to secure vascular access in a patient with severe factor V deficiency and intracranial haemorrhage” Submitted to Haemophilia
  36. Barnes, C Gordon, A Monagle, P Anderson, V Hunt, R Coleman, L Ditchfield, M Rice, J Kornberg, A and Mackay, M “Development of a paediatric stroke program– principles and process” Submitted to Medical Journal of Australia
  37. Vijayasekaran, V Barnes, C Monagle, P Phillips, G Pennington A and Coombs C “Compartment syndrome secondary to spontaneous thrombosis of a venous malformation following Varicella infection” Submitted to Thrombosis and Haemostasis

Books

  • Barnes, C Newall, F and Monagle, P “Strokes in Kids” Parent information book, Royal Childrens Hospital 2000

Book Chapters

  • Barnes, C and Ashley, D.  Cancer in children, In Paediatric Chiropractics 2000. Editor N Davies Churchill-Livingstone Chapter 17 243 - 264.

Posters / Abstracts

  1. Barnes C and Ekert H. Immunotolerance of inhibitors to Factor IX using plasmapheresis and challenge with highly purified Factor IX. Presented at XXIII International Congress of the World Federation of Haemophilia May 1998.
  2. Barnes C, Newall F, Savoia H, Campbell J and Monagle, P. Twelve months experience of a paediatric thrombosis program Royal Australian College of Physicians Annual Scientific Meeting May 2001
  3. Barnes C, Downie P, Chalikiadis G Camilleri S, Monagle P and Waters, K Sedation Practices for Australian and New Zealand Paediatric Oncology Patients American Society of Haematology Annual Meeting December 2001
  4. Monagle, P Barnes C, Newall F, Savoia H, Campbell J and Smith PJ. Twelve months experience of a paediatric thrombosis program. American Society of Haematology Annual Meeting December 2001
  5. Monagle P Barnes C, Newall F, Chan, A MTHFR mutation in childhood stroke. American Society of Haematology Annual Meeting December 2001
  6. Monagle P, Barnes C, Newall F and Smith PJ. Post thrombotic syndrome in children. American Society of Haematology Annual Meeting December 2001
  7. Monagle P, Barnes C, Newall F, Chan, A. Prothrombin gene mutation and childhood stroke. American Society of Haematology Annual Meeting December 2001
  8. Monagle, P Barnes, C Ignjatovic, V Ng, F Newall, F Hamilton, S Waters, K Ashley, D “A change in serum procalcitonin over twenty four hours predicts the clinical outcome of children admitted with febrile neutropenia”. American Society of Haematology Annual Meeting December 2001
  9. Monagle, P Newall, F Barnes, C Bines, J Heine, R Auldist, A Savoia, H Campbell, J Ignatovic, V Smith, P. "Warfarin as central line prophylaxis in children on home total parentaral nutriton". American Society of Haematology Annual Meeting December 2001
  10. Monagle, P Newall, F Barnes, C Savoia, H Campbell, J Smith P “The Role of Inherited Thrombophilic Markers in Paediatric Thrombosis Is over Interpreted”. American Society of Haematology Annual Meeting December 2001
  11. Barnes, C Brewin, T Monagle, P Ekert, H Epidural haemorrhage in patients with severe haemophilia and inhibitors; a review of management options. World Federation of Haemophilia Congress Seville 2002
  12. Barnes, C  Ignjatovic, V Ng, F Newall, F Hamilton, S Waters, K Ashley, D Monagle, P “A change in serum procalcitonin over twenty four hours predicts the clinical outcome of children admitted with febrile neutropenia”. Royal Australian College of Physicians Annual Scientific Meeting May 2002
  13. Ignjatovic, V Barnes, C De Rosa, L and Monagle, P “Platelet function in relation to mild-moderate thrombocytopenia as assessed by PFA-100” Royal Australian College of Physicians Annual Scientific Meeting May 2002
  14. Monagle, P Newall, F Wong, P Barnes, C Ignjatovic, V and Cameron, F. “A Cross-sectional survey of Bone Densitometry in Children on Long term Warfarin” American Society of Haematology Annual Meeting December 2002
  15. Monagle, P Ignatovic, V Barnes, C Newall, F Campbell, J and Savoia, H “The Importance of Age-appropriate Reference Intervals” American Society of Haematology Annual Meeting December 2002
  16. Monagle, P Ignatovic, V, Newall, F Barnes, C Hamilton, S and Burgess, J. “Point of Care Monitoring of Oral Anticoagulant Therapy in Children: Comparison of Coaguchek Plus and Thrombotest Methods with Venous International Ratio (INR)”. American Society of Haematology Annual Meeting December 2002
  17. Monagle P, Newall F, Savoia H, Campbell J, Browne M, Greenway A, Crock C, Barnes C “Arterial thromboembolic disease in infants and children.” ISTH Congress, 2003.
  18. Monagle P, Ignjatovic V, Barnes C, Newall F, Campbell J, Savoia H. “Reference ranges for haemostatic parameters in children” ISTH Congress, 2003.
  19. Barnes, C Wong, P Egan, B Brewin, T Cameron, F Jones, G Monagle, P and Ekert, H “Bone density in children with severe haemophilia” American Society of Hematology Annual Meeting December 2003
  20. Barnes, C Rivard, G Poon, MC Teitel, J, Pai, M Kern, M Blanchette, V and Carcao, M on behalf of the Inhibitor Subcommittee of the Association of Haemophilia Clinic Directors of Canada “Canadian multi-institutional survey of immune tolerance therapy (ITT) – experience with the use of recombinant factor VIII for ITT” Submitted to the International Congress of the World Federation Haemophilia, October 2004
  21. Barnes, C Stain, MA Hilliard, Pazmino-canizares, J Clark, D Blanchette, V and Carcao, M “Triplets with moderate haemophilia A: disease phenotype is more than just the mutation.” Submitted to the International Congress of the World Federation Haemophilia, October 2004
  22. Barnes, C Blanchette, V Canning, P and Carcao, M “Recombinant FVIIa in the management of intracerebral hemorrhage in severe thrombocytopenia unresponsive to platelet enhancing treatment” Submitted to the International Congress of the World Federation Haemophilia, October 2004
  23. Ignjatovic, V Furmedge, J Barnes, C Newall, F and Monagle, P “Reference Ranges for Haemostatic parameters in Healthy Australian Neonates” HSANZ/ASBT/ASTH Conference, October 2004
  24. Ignjatovic, V Furmedge, J Newall, F Barnes, C Burgess, J and Monagle, P  “Comparison of two Point of Care International Normalised Ratio measurements in Children” HSANZ/ASBT/ASTH Conference, October 2004
  25. Price, V Barnes, C Canning, P Blanchette, V and Greenberg, M “Immune thrombocytopenia following cancer in children” Submitted to Pediatric Oncology Group of Ontario Annual Conference, Toronto 2004
  26. Barnes, C Hilliard, P Stain, AM Floros, G Blanchette, V and Carcao, M “Care of immigrant children with haemophilia” Submitted to the Annual Meeting of the American Society of Hematology, San Diego 2004
  27. Barnes, C Szentandrassy, J Furmedge, J Egan, B Ekert, H and Monagle, P “Obesity in children with haemophilia – a substantial problem?” Submitted to the World Federation of Haemophilia, Vancouver 2006
  28. Peake, L Francis, D Monagle P and Barnes, C “Urgent arteriovenous fistula to secure vascular access in a patient with severe factor V deficiency and intracranial haemorrhage”. Submitted to the World Federation of Haemophilia, Vancouver 2006
  29. Davis, A Furmedge, J Szentrandrassy, J Monagle, P and Barnes C “Induction of immune tolerance using Rituximab in a child with severe haemophilia B with inhibitors and anaphylaxis to factor IX” Submitted to the World Federation of Haemophilia, Vancouver 2006

 

Scholarships / Prizes

  • Ansell Mechai Scholarship for Medical Student Elective 1990
  • Kids Oncology and Leukaemia Action Group / Scott Freeman Travel Grant 1999
  • Jeannie Poolman Travelling Scholarship 2000
  • National Health and Medical Research Council Medical Postgraduate Research Scholarship 2001
  • Royal College of Pathologists of Australasia Travel Grant 2001
  • Royal College of Pathologists of Australasia Travel Grant 2003
  • First Prize Clinical Research, Resident Research Competition 2004, The Hospital for Sick Children, Toronto, Canada

Grants

  • Government of Victoria, Department Health and Community Services New Technologies Grant 1997/8 “Stem Cell Supported Chemotherapy at the Royal Children’s Hospital”
  • Government of Victoria, Department Health and Community Services New Technologies Grant 1998/9 “Stem Cell Supported Chemotherapy at the Royal Children’s Hospital”
  • Murdoch Children’s Research Institute Grant 2000 “The role of Procalcitonin in discriminating bacterial sepsis in febrile neutropenic children”
  • Murdoch Children’s Research Institute Grant 2001“A cross sectional survey of bone density in children with severe haemophilia”
  • Heart Kids Victoria Research Grant 2001“Monitoring the antiplatelet effect of aspirin in children with the Platelet Function Analyser (PFA – 100)”.
  • Bayer Industry supported grant “Rapidpoint, point of care monitoring in children”, 2002
  • Baxter Bioscience Haemostasis Fellowship Grant, The Hospital For Sick Children, Toronto, Canada
  • Haemophilia Foundation of Australia Grant “Head injury in children with haemophilia – predictors of clinical outcome”
  • Haemophilia Foundation of Australia Grant “Thrombin generation, the role of hyperfibrinolysis (levels of Thrombin Activatable Fibrinolysis Inhibitor; TAFI) and levels of Tissue Factor Pathway Inhibitor (TFPI) in children with severe Haemophilia: correlation to clinical outcomes”.


Reviewer

  • Blood
  • Thrombosis and Haemostasis